Comparative genomic analysis of three intestinal species reveals reductions in secreted pathogenesis determinants in bovine-specific and non-pathogenic Cryptosporidium species.

The three common intestinal Cryptosporidium species in cattle differ significantly in host range, pathogenicity and public health significance. While Cryptosporidium parvum is pathogenic in pre-weaned calves and has a broad host range, C. bovis and C. ryanae are largely non-pathogenic and bovine-specific species in post-weaned calves.

Thus far, only the genome of C. parvum has been sequenced. To improve our understanding of the genetic determinants of biological differences among Cryptosporidium spcies, we sequenced the genomes of C. bovis and C. ryanae and conducted a comparative genomics analysis.

The genome of C. bovis has a gene content and organization more similar to C. ryanae than to other Cryptosporidium species sequenced to date; the level of similarity in amino acid and nucleotide sequences between the two species is 75.2 and 69.4 %, respectively. A total of 3723 and 3711 putative protein-encoding genes were identified in the genomes of C. bovis and C. ryanae, respectively, which are fewer than the 3981 in C. parvum. Metabolism is similar among the three species, although energy production pathways are further reduced in C. bovis and C. ryanae. Compared with C. parvum, C. bovis and C. ryanae have lost 14 genes encoding mucin-type glycoproteins and three for insulinase-like proteases.

Other gene gains and losses in the two bovine-specific and non-pathogenic species also involve the secretory pathogenesis determinants (SPDs); they have lost all genes encoding MEDLE, FLGN and SKSR proteins, and two of the three genes for NFDQ proteins, but have more genes encoding secreted WYLE proteins, secreted leucine-rich proteins and GPI-anchored adhesin PGA18.

Goat anti Mouse IgM
FNSA-0091	FN Test	500 uL	EUR 367.92
Description: Goat anti Mouse IgM secondary antibody

GOAT ANTI MOUSE IgM
MBS220492-1mg	MyBiosource	1mg	EUR 500

GOAT ANTI MOUSE IgM
MBS220492-5x1mg	MyBiosource	5x1mg	EUR 2065

GOAT ANTI MOUSE IgM
MBS235262-1mg	MyBiosource	1mg	EUR 365

GOAT ANTI MOUSE IgM
MBS235262-5x1mg	MyBiosource	5x1mg	EUR 1465

Goat anti Mouse IgM
MBS539831-2mg	MyBiosource	2mg	EUR 490

Goat anti Mouse IgM
MBS539831-5x2mg	MyBiosource	5x2mg	EUR 2055

Rabbit anti Mouse IgM
20-B80010000-U4	Fitzgerald	10 ml	EUR 150
Description: Rabbit anti Mouse IgM antibody

Rabbit anti Mouse IgM
40C-CB1506	Fitzgerald	2 mg	EUR 277
Description: Rabbit anti Mouse IgM secondary antibody

Rabbit anti Mouse IgM
40-B9201R000-R0	Fitzgerald	5 ml	EUR 95
Description: Rabbit anti Mouse IgM secondary antibody

Mouse anti Rat IgM
41R-1122	Fitzgerald	100 ug	EUR 218
Description: Mouse anti Rat IgM secondary antibody

Mouse anti Rat IgM
41R-1123	Fitzgerald	100 ug	EUR 218
Description: Mouse anti Rat IgM secondary antibody

MOUSE ANTI PIG IgM
MBS224786-01mg	MyBiosource	0.1mg	EUR 410

MOUSE ANTI PIG IgM
MBS224786-5x01mg	MyBiosource	5x0.1mg	EUR 1670

Mouse anti Human IgM
10-I20A	Fitzgerald	1 mg	EUR 1984
Description: Mouse anti Human IgM antibody

Mouse anti Human IgM
10-I20B	Fitzgerald	1 mg	EUR 245
Description: Mouse anti Human IgM antibody

Mouse anti Human IgM
10-I20G	Fitzgerald	1 mg	EUR 245
Description: Mouse anti Human IgM antibody

Mouse anti Human IgM
10-I20H	Fitzgerald	1 mg	EUR 145
Description: Mouse anti Human IgM antibody

Mouse anti Human IgM
10R-I130a	Fitzgerald	1 mg	EUR 268
Description: Mouse anti Human IgM antibody

Mouse anti Human IgM
10R-I130B	Fitzgerald	1 mg	EUR 360
Description: Mouse anti Human IgM antibody

Mouse anti Human IgM
10C-CR2023M2	Fitzgerald	1 mg	EUR 140
Description: Mouse anti Human IgM antibody

Mouse anti Human IgM
10C-CR2023M3	Fitzgerald	1 mg	EUR 138
Description: Mouse anti Human IgM antibody

Mouse anti Human IgM
41R-1586	Fitzgerald	100 ug	EUR 218
Description: Monoclonal Mouse anti Human IgM antibody

Mouse anti Human IgM
40R-1005	Fitzgerald	100 ug	EUR 218
Description: Mouse anti Human IgM antibody

Mouse Anti Human IgM
E61I00402	EnoGene	100ug	EUR 225

Mouse Anti Human IgM
MBS122131-01mg	MyBiosource	0.1mg	EUR 175

Mouse Anti Human IgM
MBS122131-1mg	MyBiosource	1mg	EUR 285

Mouse Anti Human IgM
MBS122131-5x1mg	MyBiosource	5x1mg	EUR 1185

Mouse Anti Human IgM
MBS8579744-01mg	MyBiosource	0.1mg	EUR 305

Mouse Anti Human IgM
MBS8579744-5x01mg	MyBiosource	5x0.1mg	EUR 1220

Mouse Anti Human IgM
MBS140500-01mg	MyBiosource	0.1mg	EUR 265

Mouse Anti Human IgM
MBS140500-05mg	MyBiosource	0.5mg	EUR 335

Mouse Anti Human IgM
MBS140500-1mg	MyBiosource	1mg	EUR 450

Mouse Anti Human IgM
MBS140500-5x1mg	MyBiosource	5x1mg	EUR 1690

MOUSE ANTI HUMAN IgM
MBS212256-02mg	MyBiosource	0.2mg	EUR 490

MOUSE ANTI HUMAN IgM
MBS212256-5x02mg	MyBiosource	5x0.2mg	EUR 2025

MOUSE ANTI HUMAN IgM
MBS211713-02mg	MyBiosource	0.2mg	EUR 490

MOUSE ANTI HUMAN IgM
MBS211713-5x02mg	MyBiosource	5x0.2mg	EUR 2025

MOUSE ANTI HUMAN IgM
MBS235340-025mg	MyBiosource	0.25mg	EUR 535

MOUSE ANTI HUMAN IgM
MBS235340-5x025mg	MyBiosource	5x0.25mg	EUR 2240

Mouse anti Human IgM
MBS531830-1mg	MyBiosource	1mg	EUR 455

Mouse anti Human IgM
MBS531830-5x1mg	MyBiosource	5x1mg	EUR 1905

Mouse anti Human IgM
MBS532538-1mg	MyBiosource	1mg	EUR 250

Mouse anti Human IgM
MBS532538-5x1mg	MyBiosource	5x1mg	EUR 975

Mouse anti Human IgM
MBS532552-1mg	MyBiosource	1mg	EUR 290

Mouse anti Human IgM
MBS532552-5x1mg	MyBiosource	5x1mg	EUR 1155

Mouse anti Human IgM
MBS532553-1mg	MyBiosource	1mg	EUR 290

Mouse anti Human IgM
MBS532553-5x1mg	MyBiosource	5x1mg	EUR 1155

Mouse anti Human IgM
MBS531227-1mg	MyBiosource	1mg	EUR 455

Mouse anti Human IgM
MBS531227-5x1mg	MyBiosource	5x1mg	EUR 1905

Mouse anti Human IgM
MBS530727-1mg	MyBiosource	1mg	EUR 505

Mouse anti Human IgM
MBS530727-5x1mg	MyBiosource	5x1mg	EUR 2115

Mouse anti Human IgM
MBS530736-1mg	MyBiosource	1mg	EUR 2365

Mouse anti Human IgM
MBS530736-5x1mg	MyBiosource	5x1mg	EUR 10500

MOUSE ANTI BOVINE IgM
MBS219935-01mg	MyBiosource	0.1mg	EUR 370

MOUSE ANTI BOVINE IgM
MBS219935-5x01mg	MyBiosource	5x0.1mg	EUR 1500

Mouse anti-human IgM
10-2867	Fitzgerald	1 mg	EUR 120
Description: Mouse anti-human IgM monoclonal antibody

MOUSE ANTI CHICKEN IgM
MBS219833-025mg	MyBiosource	0.25mg	EUR 510

MOUSE ANTI CHICKEN IgM
MBS219833-5x025mg	MyBiosource	5x0.25mg	EUR 2115

Mouse anti-human IgM
MBS355902-1mg	MyBiosource	1mg	EUR 235

Mouse anti-human IgM
MBS355902-5x1mg	MyBiosource	5x1mg	EUR 755

Goat anti Mouse IgM (HRP)
43C-CB5118	Fitzgerald	1 mg	EUR 385
Description: Goat anti Mouse IgM secondary antibody (HRP)

Goat anti Mouse IgM (HRP)
MBS538758-1mg	MyBiosource	1mg	EUR 665

Goat anti Mouse IgM (HRP)
MBS538758-5x1mg	MyBiosource	5x1mg	EUR 2850

Goat anti Mouse IgM (FITC)
60-GM33	Fitzgerald	2 mg	EUR 325
Description: Goat anti Mouse IgM secondary antibody (FITC)

Goat anti Mouse IgM (FITC)
43C-CB5114	Fitzgerald	2 mg	EUR 329
Description: Goat anti Mouse IgM secondary antibody (FITC)

Rabbit anti Mouse IgM (u)
MBS316430-2mg	MyBiosource	2mg	EUR 605

Rabbit anti Mouse IgM (u)
MBS316430-5x2mg	MyBiosource	5x2mg	EUR 2550

Goat anti Mouse IgM (FITC)
MBS538754-2mg	MyBiosource	2mg	EUR 595

Goat anti Mouse IgM (FITC)
MBS538754-5x2mg	MyBiosource	5x2mg	EUR 2515

Goat anti Mouse IgM (FITC)
MBS534667-2mg	MyBiosource	2mg	EUR 560

Goat anti Mouse IgM (FITC)
MBS534667-5x2mg	MyBiosource	5x2mg	EUR 2370

Rabbit anti Mouse IgM (HRP)
43C-CB5111	Fitzgerald	1.5 mg	EUR 389
Description: Rabbit anti Mouse IgM secondary antibody (HRP)

Rabbit anti Mouse IgM (HRP)
MBS538753-15mg	MyBiosource	1.5mg	EUR 685

Rabbit anti Mouse IgM (HRP)
MBS538753-5x15mg	MyBiosource	5x1.5mg	EUR 2925

Rabbit anti Mouse IgM (FITC)
43C-CB5107	Fitzgerald	1.5 mg	EUR 270
Description: Rabbit anti Mouse IgM secondary antibody (FITC)

Goat anti Mouse IgM (biotin)
43C-CB5117	Fitzgerald	2 mg	EUR 365
Description: Goat anti Mouse IgM secondary antibody (biotin)

Rabbit anti Mouse IgM (FITC)
MBS538750-15mg	MyBiosource	1.5mg	EUR 490

Rabbit anti Mouse IgM (FITC)
MBS538750-5x15mg	MyBiosource	5x1.5mg	EUR 2055

Goat anti Mouse IgM (biotin)
MBS538757-2mg	MyBiosource	2mg	EUR 735

Goat anti Mouse IgM (biotin)
MBS538757-5x2mg	MyBiosource	5x2mg	EUR 3160

Mouse anti-sulfatide antibody (IgM) (anti-Sul IgM) ELISA Kit
MBS2603886-10x96StripWells	MyBiosource	10x96-Strip-Wells	EUR 3290

Mouse anti-sulfatide antibody (IgM) (anti-Sul IgM) ELISA Kit
MBS2603886-48StripWells	MyBiosource	48-Strip-Wells	EUR 295

Mouse anti-sulfatide antibody (IgM) (anti-Sul IgM) ELISA Kit
MBS2603886-5x96StripWells	MyBiosource	5x96-Strip-Wells	EUR 1800

Mouse anti-sulfatide antibody (IgM) (anti-Sul IgM) ELISA Kit
MBS2603886-96StripWells	MyBiosource	96-Strip-Wells	EUR 450

Rabbit anti Mouse IgM (biotin)
43C-CB5110	Fitzgerald	1.5 mg	EUR 362
Description: Rabbit anti Mouse IgM secondary antibody (biotin)

Rabbit anti Mouse IgM (biotin)
MBS539139-15mg	MyBiosource	1.5mg	EUR 645

Rabbit anti Mouse IgM (biotin)
MBS539139-5x15mg	MyBiosource	5x1.5mg	EUR 2755

Goat anti Mouse IgM (rhodamine)
43C-CB5115	Fitzgerald	2 mg	EUR 319
Description: Goat anti Mouse IgM secondary antibody (Rhodamine)

Goat anti Mouse IgM (rhodamine)
MBS538755-2mg	MyBiosource	2mg	EUR 565

Goat anti Mouse IgM (rhodamine)
MBS538755-5x2mg	MyBiosource	5x2mg	EUR 2395

Goat anti Mouse IgG + IgM
41R-1063	Fitzgerald	1 mg	EUR 115
Description: Goat anti Mouse IgG + IgM secondary antibody

Goat anti Mouse IgG + IgM
41R-1064	Fitzgerald	1 mg	EUR 176
Description: Goat anti Mouse IgG + IgM secondary antibody

Rabbit anti Mouse IgM (rhodamine)
43C-CB5108	Fitzgerald	1.5 mg	EUR 277
Description: Rabbit anti Mouse IgM secondary antibody (Rhodamine)

Rabbit anti Mouse IgM (rhodamine)
MBS538751-15mg	MyBiosource	1.5mg	EUR 505

Rabbit anti Mouse IgM (rhodamine)
MBS538751-5x15mg	MyBiosource	5x1.5mg	EUR 2125

Anti-Normal Mouse IgM Antibody
MBS4158481-01mg	MyBiosource	0.1mg	EUR 1055

Anti-Normal Mouse IgM Antibody
MBS4158481-5x01mg	MyBiosource	5x0.1mg	EUR 4485

Mouse anti Rat IgM (HRP)
43R-1632	Fitzgerald	100 ug	EUR 233
Description: Mouse anti Rat IgM secondary antibody (HRP)

Mouse anti Rat IgM (HRP)
43R-1633	Fitzgerald	100 ug	EUR 233
Description: Mouse anti Rat IgM secondary antibody (HRP)

Mouse anti Human IgM (HRP)
43R-1586	Fitzgerald	100 ug	EUR 233
Description: Mouse anti Human IgM antibody (HRP)

Mouse Anti-Rat IgM-PE
MBS673767-01mg	MyBiosource	0.1mg	EUR 325

Mouse Anti-Rat IgM-PE
MBS673767-5x01mg	MyBiosource	5x0.1mg	EUR 1315

Mouse anti Human IgM antibody
10R-1975	Fitzgerald	100 ul	EUR 268
Description: Mouse anti Human IgM antibody

Mouse anti-Cow IgM Antibody
abx401342-01mg	Abbexa	0.1 mg	EUR 543.6

Mouse anti-Pig IgM Antibody
abx401401-01mg	Abbexa	0.1 mg	EUR 610.8

Mouse Anti-Cow IgM Antibody
abx401342-100g	Abbexa	100 µg	Ask for price

Mouse Anti-Cow IgM Antibody
abx401342-25g	Abbexa	25 µg	EUR 337.5

Mouse Anti-Pig IgM Antibody
abx401401-100g	Abbexa	100 µg	EUR 400

Mouse anti Human IgM antibody
MBS831061-01mL	MyBiosource	0.1mL	EUR 510

Mouse anti Human IgM antibody
MBS831061-5x01mL	MyBiosource	5x0.1mL	EUR 2135

Anti-Human IgM Mouse mAb
E2201077	EnoGene	100ul	EUR 225
Description: Available in various conjugation types.

Mouse Anti-KLH IgM ELISA
KT-565	Kamiya Biomedical Company	96 tests	EUR 723

Mouse Anti-DNP IgM ELISA
KT-673	Kamiya Biomedical Company	96 tests	EUR 723

Mouse Anti-PEG IgM ELISA
KT-676	Kamiya Biomedical Company	96 tests	EUR 723

Mouse Anti-TNP IgM ELISA
KT-691	Kamiya Biomedical Company	96 tests	EUR 723

Mouse Anti-Rat IgM-HRP
MBS673765-1mL	MyBiosource	1mL	EUR 420

Mouse Anti-Rat IgM-HRP
MBS673765-5x1mL	MyBiosource	5x1mL	EUR 1740

Mouse Anti-Rat IgM-CY5
MBS673768-01mg	MyBiosource	0.1mg	EUR 430

Mouse Anti-Rat IgM-CY5
MBS673768-5x01mg	MyBiosource	5x0.1mg	EUR 1795

Anti-Human IgM Mouse mAb
MBS8533151-01mL	MyBiosource	0.1mL	EUR 305

Anti-Human IgM Mouse mAb
MBS8533151-01mLAF405L	MyBiosource	0.1mL(AF405L)	EUR 565

Anti-Human IgM Mouse mAb
MBS8533151-01mLAF405S	MyBiosource	0.1mL(AF405S)	EUR 565

Anti-Human IgM Mouse mAb
MBS8533151-01mLAF610	MyBiosource	0.1mL(AF610)	EUR 565

Anti-Human IgM Mouse mAb
MBS8533151-01mLAF635	MyBiosource	0.1mL(AF635)	EUR 565

Anti-Human IgM Mouse mAb
MBS475156-01mL	MyBiosource	0.1mL	EUR 450

Anti-Human IgM Mouse mAb
MBS475156-5x01mL	MyBiosource	5x0.1mL	EUR 1540

Anti-Human IgM Mouse mAb
MBS477395-01mL	MyBiosource	0.1mL	EUR 450

Anti-Human IgM Mouse mAb
MBS477395-5x01mL	MyBiosource	5x0.1mL	EUR 1540

Anti-Human IgM Mouse mAb
MBS477396-01mL	MyBiosource	0.1mL	EUR 450

Anti-Human IgM Mouse mAb
MBS477396-5x01mL	MyBiosource	5x0.1mL	EUR 1540

Mouse Anti-Human IgM Antibody
20-abx134803	Abbexa	Ask for price Ask for price	100 ul 500 ul

Mouse Anti-Sheep IgM Antibody
abx023343-1mg	Abbexa	1 mg	EUR 661.2

Mouse Anti-Human IgM Antibody
abx023365-1mg	Abbexa	1 mg	EUR 794.4

Mouse Anti-Human IgM Antibody
abx023388-1mg	Abbexa	1 mg	EUR 718.8

IgM Antibody, Mouse anti-Human
GWB-IGM003	GenWay Biotech	0.1 mg	Ask for price

Mouse Anti-Human IgM Antibody
abx023365-400l	Abbexa	400 µl	Ask for price

Mouse Anti-Human IgM Antibody
abx023365-80l	Abbexa	80 µl	EUR 1050

Mouse Anti-Human IgM Antibody
abx023388-400l	Abbexa	400 µl	Ask for price

Mouse Anti-Human IgM Antibody
abx023388-80l	Abbexa	80 µl	EUR 675

Mouse Anti-Human IgM Antibody
abx134803-01mg	Abbexa	0.1 mg	EUR 187.5

Mouse Anti-Human IgM antibody
STJ99547-100l	St John's Laboratory	100 µl	EUR 97.2
Description: Unconjugated Mouse monoclonal to Human IgM antibody

Mouse Anti-Human IgM antibody
STJ99547-1mL	St John's Laboratory	1 mL	EUR 475.2
Description: Unconjugated Mouse monoclonal to Human IgM antibody

PE mouse anti-Chicken IgM
E16SMP408-100U	EnoGene	100 μg	EUR 931.67
Description: Available in various conjugation types.

Mouse Anti-SRBC IgM ELISA
KT-573	Kamiya Biomedical Company	96 tests	EUR 723

Mouse Anti-Rat IgM-UNLB
MBS673763-05mg	MyBiosource	0.5mg	EUR 290

Mouse Anti-Rat IgM-UNLB
MBS673763-5x05mg	MyBiosource	5x0.5mg	EUR 1155

Mouse Anti-Rat IgM-FITC
MBS673764-05mg	MyBiosource	0.5mg	EUR 345

Mouse Anti-Rat IgM-FITC
MBS673764-5x05mg	MyBiosource	5x0.5mg	EUR 1395

Mouse Anti-Human IgM-AP
MBS673989-1mL	MyBiosource	1mL	EUR 315

Mouse Anti-Human IgM-AP
MBS673989-5x1mL	MyBiosource	5x1mL	EUR 1275

Mouse Anti-Human IgM-PE
MBS673992-01mg	MyBiosource	0.1mg	EUR 305

Mouse Anti-Human IgM-PE
MBS673992-5x01mg	MyBiosource	5x0.1mg	EUR 1215

Mouse Anti-Human IgM-AP
MBS673996-1mL	MyBiosource	1mL	EUR 315

Mouse Anti-Human IgM-AP
MBS673996-5x1mL	MyBiosource	5x1mL	EUR 1275

Mouse Anti-Human IgM-PE
MBS673999-01mg	MyBiosource	0.1mg	EUR 305

Mouse Anti-Human IgM-PE
MBS673999-5x01mg	MyBiosource	5x0.1mg	EUR 1215

Mouse anti cardiolipin antibody IgM,ACA IgM ELISA kit
E03A2052-192T	BlueGene	192 tests	EUR 1524
Description: A sandwich ELISA for quantitative measurement of Mouse anti cardiolipin antibody IgM,ACA IgM in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse anti cardiolipin antibody IgM,ACA IgM ELISA kit
E03A2052-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A sandwich ELISA for quantitative measurement of Mouse anti cardiolipin antibody IgM,ACA IgM in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse anti cardiolipin antibody IgM,ACA IgM ELISA kit
E03A2052-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A sandwich ELISA for quantitative measurement of Mouse anti cardiolipin antibody IgM,ACA IgM in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Anti-Human IgM - AF350
L35132	SAB	100 ul	EUR 59

Mouse Anti-Human IgM - AF405
L35175	SAB	100 ul	EUR 59

Mouse Anti-Human IgM - AF488
L35218	SAB	100 ul	EUR 59

Mouse Anti-Human IgM - AF532
L35261	SAB	100 ul	EUR 59

Mouse Anti-Human IgM - AF555
L35304	SAB	100 ul	EUR 59

Mouse Anti-Human IgM - AF568
L35347	SAB	100 ul	EUR 59

Mouse Anti-Human IgM - AF594
L35390	SAB	100 ul	EUR 59

Mouse Anti-Human IgM - AF633
L35433	SAB	100 ul	EUR 59

Mouse Anti-Human IgM - AF647
L35476	SAB	100 ul	EUR 59

Mouse Anti-Human IgM - AF660
L35519	SAB	100 ul	EUR 59

Mouse Anti-Human IgM - AF680
L35562	SAB	100 ul	EUR 59

Mouse Anti-Human IgM - AF750
L35605	SAB	100 ul	EUR 79

Mouse Anti-Human IgM - AF790
L35648	SAB	100 ul	EUR 79

Mouse Anti-Human IgM-HRP
MBS673990-1mL	MyBiosource	1mL	EUR 310

Mouse Anti-Human IgM-HRP
MBS673990-5x1mL	MyBiosource	5x1mL	EUR 1240

Mouse Anti-Human IgM-APC
MBS673993-01mg	MyBiosource	0.1mg	EUR 385

Mouse Anti-Human IgM-APC
MBS673993-5x01mg	MyBiosource	5x0.1mg	EUR 1575

Mouse Anti-Human IgM-HRP
MBS673997-1mL	MyBiosource	1mL	EUR 310

Mouse Anti-Human IgM-HRP
MBS673997-5x1mL	MyBiosource	5x1mL	EUR 1240

Goat anti Mouse IgM (H + L)
41R-1062	Fitzgerald	2 mg	EUR 250
Description: Goat anti Mouse IgM (H + L) secondary antibody

Mouse Anti-myocardial antibody (IgM)(HRAb IgM) ELISA Kit
NSL1495m	Sunlong	96 Test	EUR 528

Mouse anti-Chicken IgM Antibody
abx401384-025mg	Abbexa	0.25 mg	EUR 710.4

Mouse Anti-Chicken IgM Antibody
abx401384-100g	Abbexa	100 µg	EUR 475

FITC mouse anti-Chicken IgM
E16SMF408-500U	EnoGene	500 μg	EUR 1473.33
Description: Available in various conjugation types.

UNLB mouse anti-Chicken IgM
E16SMU408-500U	EnoGene	500 μg	EUR 1040
Description: Available in various conjugation types.

Mouse Anti-Chicken IgM-PE
MBS673915-01mg	MyBiosource	0.1mg	EUR 325

Mouse Anti-Chicken IgM-PE
MBS673915-5x01mg	MyBiosource	5x0.1mg	EUR 1315

The only major difference between C. bovis and C. ryanae is in nucleotide metabolism. In addition, half of the highly divergent genes between C. bovis and C. ryanae encode secreted or membrane-bound proteins. Therefore, C. bovis and C. ryanae have gene organization and metabolic pathways similar to C. parvum, but have lost some invasion-associated mucin glycoproteins, insulinase-like proteases, MEDLE secretory proteins and other SPDs.

The multiple gene families under positive selection, such as helicase-associated domains, AMP-binding domains, protein kinases, mucins, insulinases and TRAPs could contribute to differences in host specificity and pathogenicity between C. parvum and C. bovis. Biological studies should be conducted to assess the contribution of these copy number variations to the narrow host range and reduced pathogenicity of C. bovis and C. ryanae.